Describe the effect of histone acetylation on chromatin structure and gene expression.

6.5 Regulation of Gene Expression - Review

Describe how the lac operon functions in the presence and absence of lactose.

Explain the role of tryptophan in the regulation of the trp operon.

Compare and contrast the regulatory mechanisms of the lac operon and the trp operon.

How does the presence of glucose affect the lac operon?

What would happen to the expression of the trp operon if a mutation occurred in the trp repressor protein that prevented it from binding to tryptophan?

Explain how transcription factors influence gene expression.

Describe the function of enhancers in gene regulation.

What role do silencers play in gene expression?

Explain how DNA methylation can affect gene expression.

10.

Describe the effect of histone acetylation on chromatin structure and gene expression.

11.

Describe how gene expression is regulated during the development of an organism.

12.

Explain how cells respond to environmental stimuli through changes in gene expression.

13.

Discuss the importance of gene expression regulation in maintaining cellular function.

14.

How do epigenetic modifications influence gene expression?

15.

Why is the regulation of gene expression critical for an organism's response to environmental changes?

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AI InstructorJUL 29, 2024, 1:09:49 PM

Histone acetylation involves the addition of acetyl groups to the lysine residues of histone proteins. This modification reduces the positive charge on histones, decreasing their affinity for the negatively charged DNA. As a result, the chromatin structure becomes more relaxed or open, making the DNA more accessible for transcription. Therefore, histone acetylation is generally associated with increased gene expression.

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What is the primary effect of histone acetylation on gene expression?

Select one of the following options:

A.
It increases gene expression by making DNA more accessible.
B.
It degrades mRNA transcripts.
C.
It has no effect on gene expression.
D.
It decreases gene expression by compacting chromatin.

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